Description
GLUCOVANCE®
Composition:
Each tablet of GLUCOVANCE 500 mg/2.5 mg contains 500 mg metformin hydrochloride and 2.5 mg of glibenclamide as active ingredients.
Indication:
Treatment of type 2 diabetes mellitus in adults as replacement for previous treatment with metformin and glibenclamide in patients whose glycaemia is stable and well controlled.
Contraindications: Glucovance must not be used lf:
- You are allergic (hypersensitive) to metformin hydrochloride, glibenclamide or other sulphonamides or any of the other ingredients of Glucovance.
- You suffer from type 1 diabetes mellitus.
- You have kidney Insufficiency or liver insufficiency..
- You drink alcohol excessively.
- You are breast-feeding or pregnant.
Adverse Effects:
- Transient visual disturbances.
- Hypoglycaemia.
- Lactic acidosis.
- Gastrointestinal disorders such as nausea. Vomiting, diarrhea abdominal pain.
- Pruritus, urticaria. maculopapular rash.
Dosage and Administration: This medicine is for adults only.
The maximum dose is 2000 mg/20 mg per day (4 tablets of Glucovance 500 mg/5 mg).
Administration: The tablets should be taken with meals. The dosage regimen should be adjusted according to the individual eating habits.